Leon gained significant popularity due to his prominent role in Resident Evil 4, which is considered one of the best games in the series and a major success critically and commercially. Additionally, Leon's appearance in other Resident Evil titles and adaptations has further solidified his status as a fan favorite.

Devious, secretive and mysterious, Nathan Kennedy is one of the most successful STOs in the B.V.T.P.G.. He is the half-brother of Leon Kennedy and the product of his mothers rape.

Common allergic reactions include skin manifestations like itching, erythema, and urticaria upon contact with hops or hops-containing products. Inhalation of hop dust during brewing or consumption of products containing hops can lead to respiratory symptoms, such as rhinitis, conjunctivitis, and asthma exacerbation.