Barber is known for her role on the sitcom Full House as Kimmy Gibbler, the best friend of D.J. Tanner, which she played from 1987 to 1995. She was at first a recurring role but shortly thereafter became a regular. After Full House ended, Barber retired from acting and started focusing on her personal life.

Simply put, Ashley outright didn't want to do it. With that understanding, Mary-Kate almost took the role just so Michelle could be a part of Fuller House, but, despite this, it boiled down to bad timing. She was eager to participate but reasoned that it wasn't going to fit in her schedule.